Bachelor's Degrees

Bioprocessing Science

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Overview

The B.S. in Bioprocessing Science prepares students for careers in the bio-industries, which create commercial products using living cells, by combining courses in the biological sciences such as biochemistry and molecular biology with the applied sciences of microbiology, analytical chemistry and process engineering. These products are used in health care, agriculture, food and fuels.

For more information about this program, please contact our undergraduate academic adviser, Ms. April Morrison or the BBS undergraduate coordinator, Dr. John Sheppard.

Curriculum

Bioprocessing Science (BS) (11BBSBS)

FRESHMAN YEAR
Fall Semester Credit Spring Semester Credit
ALS 103 Transitions & Diversity  
BIO 183 or BIO 181 Intro Biology
ENG 101 Academic Writing & Research
COM 110 or COM 112
GEP Social Science
HES_*** Health & Exercise Studies
1
4
4
3
3
1
CH 101 – A Molecular Science
CH 102 General Chemistry Lab
BBS 201 Intro to Biopharm Sci
MA 131 Calc Life & Mgmnt Sciences A
Free Elective
GEP Humanities
3
1
3
3
3
3
SOPHOMORE YEAR
Fall Semester Credit Spring Semester Credit
CH 221 Organic Chemistry I
CH 222 Organic Chemistry I Lab
MA 231 Calc Life and Management Sciences B
PY 211 College Physics I
BEC 220 Intro Drug Develop & Careers or FS 290 Careers Food&Bioprocess
GEP Interdisciplinary Perspectives
3
1
3
4
13
CH 223 Organic Chemistry II
CH 224 Organic Chemistry II Laboratory
FS 231 Principles of Food & Bioprocess Engr
PY 212 College Physics II
Free Elective
3
1
4
4
3
JUNIOR YEAR
Fall Semester Credit Spring Semester Credit
CH 201 Chemistry-Quantitative Science
CH 202 Quantitative Chemistry Lab
MB 351 General Microbiology
MB 352 General Microbiology Lab
Free Elective
Anatomy/Physiology Elective
3
1
3
1
3
4
BCH 351 Elementary Biochemistry
BEC 330 Principles of Bioseparations
BEC/BIT Elective
BEC 440 Manipulation of Recomb DNA or BIT 410 Expression Systems in Bioman
GEP Additional Breadth
4
2
2
3-43
SENIOR YEAR
Fall Semester Credit Spring Semester Credit
ST 311 Introduction to Statistics
BBS 301 Process Validation Science
BBS 426 Upstream Biomanufacturing Lab
BEC 480 cGMP Fermentation Ops
GEP Humanities
HES_*** Health & Exercise Studies
3
3
2
2
3
1
FS 475 Probs & Design in Food & Bioprocess
FS 416 Quality Control Food & Bioprocess
FS 403 Analytical Techniques
GEP Social Science Requirement
GEP Interdisciplinary Perspectives
3
3
4
3
2
Minimum Credit Hours Required for Graduation: 120

 

Selected BBS/BEC/BIT Course Descriptions

(See the course catalog for prerequisites, restrictions, credit hours, and semesters offered)

BBS 201: Introduction to Biopharmaceutical Science

Through this course, students will experience laboratory and manufacturing terminology relevant to the biomanufacturing industries. Students will also gain exposure to regulatory and compliance procedures and issues facing this industry. This course will provide an introduction to prepare students to meet the demands and expectations of this industry and the bioprocessing science program.

BBS 301: Process Validation Science

Process validation is a tested and documented subset of the panel of activities that are performed during the production of a biopharmaceutical. This course will introduce the concept of process validation as it applies to the biotechnology industry, and more specifically, to the manufacture of protein molecules as therapeutic agents.

BBS 426: Upstream Biomanufacturing Laboratory

This course is an introduction to current food manufacturing practice [CGMP] as applied to the growth of microbial cells in bioreactors. Hands-on experience is obtained in the operation and control of 30 liter bioreactors to study agitation, oxygen transfer, cleaning, sterilization, media preparation and the growth of recombinant E. coli for protein production.

BEC 220: Introduction to Drug Development and Careers in Biomanufacturing

Introduction to discovery and development of biopharmaceuticals, industrial enzymes, food ingredients and biologics. Discussion of majors that prepare students for positions in the biotechnology industry. Lectures from staff and from professionalism the biotechnology industry focus on drug development, biopharmaceutical process development, design of biomanufacturing facilities, overview of methods used for manufacturing biopharmaceuticals, drug and enzyme purification, formulation, as well as careers in FDA compliance documentation related to manufacturing products using microbial biotechnology.

BEC 330: Principles and Applications of Bioseparations

Objectives, strategies, and approaches for recovery and purification of biomolecules, especially recombinant proteins. Description of common purification equipment, processes and materials used for cell lysis, precipitation, flocculation, membrane filtration, column chromatography, and centrifugation. Laboratories provide students with exposure to various techniques and the parameters that control protein isolation and purification of a recombinant protein. This is a half-semester course. Students who have completed BIT(CHE) 464 may not complete this course for credit.

BEC 440: Expression Systems in Biomanufacturing

Introduction to bacterial and yeast expression systems, their advantages and disadvantages. Basic techniques in molecular biology, cell transformation and optimization of protein expression. Selection, archiving and characterization of production line. Study of parameters affecting expression and yield. The lab portion of the course provides students with practical experience in DNA and protein expression techniques in bacterial and yeast expression systems.

BEC 480: cGMP Fermentation Operations  

Application of microbial fermentation techniques at production scale and evaluation of the inherent issues resulting from the integration of microbial fermentation unit operations, scale-up/production, and current Good Manufacturing (cGMP) compliance. Lectures prepare students for pilot-scale laboratory experiences in media preparation, bioreactor operation, process utilities, and manufacturing quality systems that simulate microbial cell growth and product expression in a commercial cGMP facility. This is a half-semester course. Students who have completed BEC 480 may not take BEC 580 for credit.

BIT 410: Manipulation of Recombinant DNA

Introduction to molecular biology and protein chemistry. Theory behind laboratory techniques and overview of cloning strategies starting from nucleic acid or protein sequence data. Laboratory sessions involve subcloning, preparation of competent cells, transformation, screening recombinant DNA by colony hybridization and PCR, SDS-PAGE of recombinant protein, affinity purification, and western blots.

Career Prospects

With a degree in Bioprocessing Science your career can range from the biopharmaceutical industry to microbiology to process control. North Carolina is fast becoming a center for bio-based businesses including pharmaceutical, agricultural and chemical manufacturers such as Bayer Crop Science, Pfizer, Syngenta, and Novozymes.

Examples of job titles and salary ranges are:

  • Laboratory Analyst $30,000-$52,000
  • Manufacturing Technician $33,000-$64,000
  • Laboratory Technologist $24,000-$57,000
  • Sales Representative $52,000-$104,000
  • Laboratory Manager $43,000-$92,000

Financial Aid & Scholarships

A wide variety of financial support is available from the department, college and university.

Learn More

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Testimonials

“During my previous experience as a veterinary technician, I became fascinated with pharmaceuticals and how drugs and vaccines kept animals healthy.  This fascination led me to explore the Bioprocessing Science major.  The curriculum offers a wide range of classes that covers different disciplines under the bioprocessing scope, including pharmaceutical research and development.  The versatility of Bioprocessing Science has also presented me with opportunities to delve into the food science discipline.  I am currently doing a research project with Dr. Kathariou in food microbiology involving the study of Campylobacter, a common foodborne pathogen in poultry farms.  In the future, I hope to investigate the industrial area of Bioprocessing Science as well.  Furthermore, the department has great mentors, faculty, and advisors to support and guide students through their undergraduate career.  I’m excited to continue to explore the many areas Bioprocessing Science has to offer as my studies in FBNS continue.” – Lynde Ring, ’16

“The FBNS Department has been excellent in exposing students to various industries. As a Junior in Bioprocessing,  guest lectures have included food science, nutrition, and pharmaceuticals. This makes the department unique because it offers students frequent insight into possible careers. The faculty, staff, and alumni have created a welcoming and comfortable environment. They are engaged with their students, provide interactive lectures, and are excited about their work. It has been an honor to be a member of this group.” – Morgan Caudill, ’15